从“邪伏子门”探讨宫颈HPV感染的机制及治疗策略

Discussion on the Mechanism and Therapeutic Strategy of Cervical HPV Infection from Xiefu Zimen

宫颈HPV感染在临床上起病隐匿、病程长、反复发作、迁延不愈,严重影响着患者的身心健康,且临床目前尚无彻底根治的方法,长期宫颈HPV感染与宫颈癌的发病呈正相关性。根据中医学伏邪理论,提出"邪伏子门"这一新的概念,认为宫颈HPV感染即等同于"病毒邪气伏于子门",简称"邪伏子门"。根据HPV正虚邪实的发病机制,及其隐匿、潜伏、缠绵难愈、易于复发等致病特点,认为可采用"扶正祛邪"的治疗原则,运用中医学"治未病"的思想,即"未病先防、欲病救萌、既病防变、瘥后防复"对其进行论治,进一步防治宫颈病变的发生及发展。

Cervical HPV infection is a kind of clinically occult,long-term,recurrent,and prolonged disease,which seriously affects the physical and mental health of the patient. At present,there is no complete cure in clinical practice. Long-term cervical HPV infection is closely related to the onset of cervical cancer. According to the theory of Fuxie(incubative pathogenic factors) in TCM,this study put forward a new concept of Fuxie Zimen(incubative pathogenic factors in external cervical orifice). It is believed that cervical HPV infection is equivalent to Fuxie Zimen. According to the pathogenesis of HPV,and its pathological characteristics of being latent and lingering,being difficult to heal and easy to relapse,it is believed that the treatment principle of supplementing vital-qi and expelling evil-qi should be applied,and the idea of prevention before disease onset,prevention before disease changing,and prevention before disease recurrence should be adopted thus to further prevent the occurrence and development of cervical lesions.