预测脑出血血肿扩大研究进展

Research progresses of prediction of hematoma enlargement of cerebral hemorrhage

自发性脑出血是死亡率最高的脑卒中,约1/3自发性脑出血患者会发生血肿扩大,提示预后不良。如在脑出血早期即可发现血肿扩大高风险患者,及时干预,可预防血肿扩大。血肿扩大的预测指标包括临床、实验室及影像学指标,对临床有效识别血肿扩大并进一步制定治疗方案有重要价值。本文对血肿扩大预测指标的预测效能及其可能机制进行综述。

Spontaneous cerebral hemorrhage is the most deadly form of stroke.About 1/3 patients with spontaneous cerebral hemorrhage undergo hematoma enlargement,which predicting a worse prognosis.If patients with high-risk of hematoma enlargement could be found and intervened in early stage,hematoma enlargement can be prevented.The predictors of hematoma enlargement include clinical index,laboratories index and imaging index,which are important for clinically effective identification of hematoma enlargement and further development of treatment options.The actual effectiveness of these predictive indicators and possible intrinsic pathogenesis were reviewed in this paper.