辅助生殖技术在单卵双胎妊娠中的临床效果及对抱婴成功率的影响研究

The clinical effect of assisted reproductive technology in monozygotic twins and the influence on the success rate of baby holding

目的探讨辅助生殖技术(assistedreproductivetechnology,ART)在单卵双胎妊娠中的临床效果及对抱婴成功率的影响研究。方法选取2013年3月-2018年3月在我院通过辅助生殖技术进行妊娠和分娩的孕产妇120例作为研究组,对其进行回顾性分析,选取在我院自然受孕分娩的孕产妇120例作为对照组,使用辅助生殖技术进行受孕分娩的孕产妇120例作为研究组,观察比较两组孕产妇的流产率、单卵双胎率、妊娠期高血压的发生率以及早产率,两组新生儿的畸形率、低体重儿率以及死亡率等情况。结果研究组孕产妇的流产率、妊娠期高血压的发生率以及早产率显著高于对照组患者(P<0.05);研究组中出现单卵双胎或者单卵三胎的出现率明显高于对照组患者(P<0.05);对照组中新生儿的畸形率、低体重儿率以及死亡率等显著低于研究组中的患者(P<0.05)。结论使用辅助生殖技术进行妊娠和生产对单卵双胎的发生以及新生儿的不良结局具有较大的风险,危害孕产妇以及新生儿的生命安全,因此,医务人员应慎重使用辅助生殖技术,进一步加强对辅助生殖技术的管理和监护。

Objective:To explore the clinical effect of assisted reproductive technology in monozygotic twin pregnancy and its influence on the success rate of baby holding.Methods:120 pregnant and lying-in women with assisted reproductive technology in our hospital from March 2013 to March 2018 were selected as study group,A retrospective analysis was made,120 pregnant women who were conceived naturally in our hospital were selected as control group,120 cases of pregnant women undergoing assisted reproductive technology were selected as the research group,Observe and compare the abortion rate,monozygotic twin rate,incidence of pregnancy induced hypertension and premature delivery rate between the two groups,Two groups of neonatal malformation rate,low birth weight rate and mortality.Results:The rate of abortion,pregnancy induced hypertension and premature delivery in the study group were significantly higher than those in the control group(P<0.05);The incidence of monozygotic twins or triplets in the study group was significantly higher than that in the control group(P<0.05);The neonatal deformity rate,low birth weight rate and mortality in the control group were significantly lower than those in the study group(P<0.05).Conclusion:Pregnancy and childbirth using assisted reproductive techniques are at greater risk for monozygotic twins and adverse outcomes in newborns,Endangering the safety of pregnant women and newborns,Therefore,Medical staff should use assisted reproductive technology cautiously,and further strengthen the management and monitoring of assisted reproductive technology.