补阳还五汤治疗稳定型心绞痛患者的临床疗效

Clinical Efficacy of Buyanghuanwu Decoction in the Treatment of Patients with Stable Angina Pectoris

目的 :探讨补阳还五汤治疗稳定型心绞痛的临床疗效。方法 :84例稳定型心绞痛(气虚血瘀证)患者按随机数字表法分为研究组及对照组,各42例。两组患者均给予西医稳定型心绞痛常规治疗,研究组在此基础上给予补阳还五汤(150 m L,bid)治疗。比较两组临床疗效、心电图疗效,及治疗前后患者心绞痛发作情况及心肌耗氧量。结果 :治疗后研究组临床总有效率和心电图有效率均显著高于对照组(P<0.05)。治疗后两组心绞痛发作频率、心绞痛持续时间和心肌耗氧量均较治疗前显著降低,研究组心绞痛发作频率、心绞痛持续时间和心肌耗氧量均低于对照组(P<0.05)。结论 :补阳还五汤可以明显改善稳定型心绞痛临床症状,并降低心肌耗氧量,治疗稳定型心绞痛有很好的疗效。

Objective:To investigate clinical efficacy of buyanghuanwu decoction in the treatment of patients with stable angina pectoris. Methods:84 patients with stable angina pectoris(qi deficiency and blood stasis syndrome) were randomly divided into study group and control group, with 42 cases in each group. Patients in both groups were given conventional western medication for the treatment of stable angina pectoris, while patients in the study group were additionally treated with buyanghuanwu decoction(150 m L, bid). The clinical curative effect, electrocardiogram(ECG) curative effect, angina pectoris attack and myocardial oxygen consumption pre or post the treatment were compared in two groups. Results:After treatment, the clinical total effective rate and the effective rate of ECG in the study group were significantly higher than those in the control group(P<0.05). The angina attack frequency, duration of angina and myocardial oxygen consumption in two groups after treatment were significantly lower than those before treatment.The angina attack frequency, duration of angina and myocardial oxygen consumption in the study group were obviously lower than those in the control group(P<0.05). Conclusion:Buyanghuanwu decoction showed good curative effect in the treatment of stable angina by improving the symptoms of stable angina and reducing myocardial oxygen consumption.