2014-2016年我院核苷类抗肝炎病毒药物应用分析

Application Analysis of Anti Hepatitis Virus Nucleoside Drugs in Our Hospital from 2014 to 2016

目的 :分析陕西省传染病院(西安市第八医院)2014-2016年核苷类抗病毒药物的应用现状及趋势,为临床合理用药提供参考。方法 :回顾性分析2014-2016年陕西省传染病医院核苷类抗肝炎病毒药物使用信息,对各类药物的销售金额、用药频度(DDDs)值、日均费用(DDC)值及药品排序比(B/A)值等进行统计分析。结果 :2014-2016年我院核苷类抗肝炎病毒药物的消耗金额呈上升趋势。恩替卡韦的销售金额和DDDs值3年来一直排名第一。2014-2016年我院核苷类抗肝炎药物的B/A值大部分接近1,表明使用频度与销售金额的同步性比较好。结论 :我院核苷类抗肝炎药物应用基本合理。

Objective:To investigate and analyze the application and development trend of anti hepatitis virus nucleoside drugs in Shanxi Province Infectious Disease Hospital(the Eighth Hospital of Xi'an City) from 2014 to 2016, and to provide reference for the clinically rational use of drugs. Methods:The retrospective analysis of anti-hepatitis virus nucleoside drugs application data in Shanxi Province Infectious Disease Hospital from 2014 to 2016 were executed. The consumption sum, defined daily doses(DDDs), defined daily cost(DDC), and drug sequence ratio(B/A) of different drugs were statistically analyzed. Results:The consumption sum of nucleoside anti-hepatitis virus agents during 2014-2016 were increased by year. Entecavir's sales amount and DDDs have been ranked first in last three years. The B/A values of the nucleoside anti-hepatitis virus drugs in our hospital during 2014-2016 were mostly closed to 1, indicating good relevance of the usage frequency and the sales amount. Conclusions:The application of nucleoside anti-hepatitis viral agents in our hospital is basically rational.