益气养阴、化瘀散结法辅助化疗对食管癌患者免疫功能及生活质量的影响

The Effect of Adjuvant Chemotherapy Combined with Yiqiyangyin and Huayu sanjie on the Immune Function and Quality of Life of Patients with Esophageal Cancer

目的 :观察益气养阴、化瘀散结法辅助化疗对食管癌患者免疫功能及生活质量的影响。方法 :选择2015年4月-2017年1月在我院确诊的中晚期食管癌患者80例,按随机数字表法分为对照组和研究组,各40例。对照组采用常规化疗,研究组在常规化疗基础上加用益气养阴、化瘀散结方,1剂/d,水煎400 m L,分为早晚两次温服。比较两组的治疗效果。结果 :两组有效率比较无统计学差异(P>0.05);治疗前两组CD4^+、CD8^+和CD4^+/CD8^+比较无统计学差异(P>0.05),治疗后研究组CD4^+、CD8^+及CD4^+/CD8^+指标改善显著优于对照组(P<0.05);治疗后研究组生活质量改善率显著高于对照组(P<0.05)。结论 :益气养阴、化瘀散结辅助化疗对于提高食管癌患者免疫功能及生活质量作用显著。

Objective:To observe the effect of adjuvant chemotherapy combined with yiqiyangyin and huayusanjie on the immune function and quality of life of patients with esophageal cancer. Methods:80 cases of middle and advanced esophageal cancer diagnosed in our hospital from April 2015 to January 2017 were selected and divided into the control group and the study group according to the random number table method, 40 cases in each group. The control group was treated with conventional chemotherapy. The study group was treated with yiqiyangyin and huayusanjie method based on conventional chemotherapy. The drugs were water fried and taken 400 m L a daily agent and divided into morning and evening. The therapeutic effects of the two groups were compared. Results:There was no significant difference in the therapeutic effects of two groups(P>0.05). There was no significant difference in CD4^+、CD8^+ and CD4^+/CD8^+ of the two groups before the treatment(P>0.05). The CD4^+ and CD8^+ and CD4^+/CD8^+ in the study group was improved significantly than that in the control group after treatment(P<0.05). After treatment, the improvement rate of quality of life in the study group was significantly higher than that in the control group(P<0.05). Conclusion:The effect of yiqiyangyin and huayusanjie method combined with adjuvant chemotherapy on improving the immune function and quality of life of the patients with esophageal cancer is significant.