泛影葡胺与欧乃派克在不孕症子宫输卵管造影检查中的应用价值比较

Comparison of Application Value of Meglumine Diatrizoate and Omnipaque in Hysterosalpingography for Infertility

目的:探讨泛影葡胺与欧乃派克在不孕症子宫输卵管造影检查中的应用价值。方法:选取2014年5月—2016年4月我院收治的80例输卵管性不孕症患者作为研究对象,按随机数字表法分为两组,各40例。对照组采用泛影葡胺(10 m L,碘浓度为76%)造影,观察组采用欧乃派克(10 m L,碘浓度为300 mg/m L)造影。观察比较两组造影图像质量、不良反应及疼痛程度。结果:观察组造影图像优良率为97.50%(39/40)高于对照组的77.50%(31/40),差异有统计学意义(P<0.05);造影后,观察组不良反应总发生率为7.50%(3/40)低于对照组的25.00%(10/40)(P<0.05);观察组视觉模拟评分法(VAS)评分低于对照组(P<0.05)。结论:在不孕症子宫输卵管造影检查中,相较于泛影葡胺,欧乃派克造影图像质量更佳,能有效减少不良反应发生率,减轻疼痛,值得临床推广。

Objective: To investigate the application value of meglumine diatrizoate and omnipaque in hysterosalpingography for infertility. Methods: 80 cases of patients with tubal infertility admitted to our hospital from May 2014 to April 2016 were selected as subjects and divided into two groups according to the random number table method, 40 cases in each group. The patients in the control group were treated with meglumine diatrizoate(10 m L, iodine concentration: 76%), and the patients in the observation group were treated with omnipaque(10 m L, iodine concentration: 300 mg/m L). The quality of the contrast images, adverse reactions and pain degree were compared between the two groups. Results: The excellent and good rate of angiographic images in the observation group was 97.50%(39/40), which was higher than 77.50%(31/40) in the control group, and the difference was statistically significant(P<0.05); after angiography, the the total incidence of adverse reactions in the observation group was 7.50%(3/40), which was lower than 25.00%(10/40) in the control group(P<0.05); the visual analog scale(VAS) in the observation group was lower than that in the control group(P<0.05).Conclusion: In hysterosalpingography for infertility, omnipaque can produce higher quality of angiographic images than meglumine diatrizoate, which can effectively reduce the incidence of adverse reactions and relieve pain, and is worthy of clinical promotion.