米力农联合地高辛治疗慢性肺源性心脏病的临床效果分析

Analysis on Clinical Effect of Milrinone Combined with Digoxin in the Treatment of Chronic Pulmonary Heart Disease

目的:分析米力农联合地高辛治疗慢性肺源性心脏病的临床效果及安全性。方法 :选取2016年3月—2017年5月我院收治的50例慢性肺源性心脏病患者,按随机数字表法分为对照组与观察组,各25例。对照组给予地高辛(0.125 mg,qd)治疗,观察组在对照组基础上给予米力农注射液(10 mg,qd)治疗,疗程均为2周。比较两组临床治疗效果、心率、肺动脉压及不良反应发生情况。结果 :观察组治疗总有效率高于对照组,心率及肺动脉压改善情况优于对照组,不良反应发生率低于对照组,差异均有统计学意义(P<0.05)。结论 :米力农联合地高辛治疗慢性肺源性心脏病疗效显著,且安全性高,值得临床推广应用。

Objective: To analyze the clinical effect and safety of milrinone combined with digoxin in the treatment of chronic pulmonary heart disease. Methods: 50 patients with chronic pulmonary heart disease admitted to our hospital from March 2016 to May 2017 were selected and randomly divided into control group and observation group, 25 cases in each group. The patients in the control group were treated with digoxin(0.125 mg, qd), and the patients in the observation group were treated with milrinone injection(10 mg, qd) on the basis of the control group. The course of treatment was 2 weeks. The clinical treatment effect, heart rate, pulmonary artery pressure and adverse reactions were compared between the two groups. Results: The total effective rate in the observation group was higher than that in the control group, the improvement of heart rate and pulmonary artery pressure was better than that in the control group, and the incidence of adverse reactions was lower than that in the control group(P<0.05). Conclusion: Milrinone combined with digoxin in the treatment of chronic pulmonary heart disease has significant efficacy and high safety, which is worthy of clinical generalization and application.