七氟醚复合麻醉与丙泊酚复合麻醉在老年关节置换术中的麻醉效果比较

Comparison of Anesthetic Effect Between Sevoflurane Combined Anesthesia and Propofol Combined Anesthesia in Elderly Joint Replacement

目的 :比较七氟醚复合麻醉与丙泊酚复合麻醉在老年关节置换术中的麻醉效果。方法 :选择我院2017年10月—2019年2月收治的100例行关节置换术的老年患者,按随机数字表法分为两组,各50例。对照组采用七氟醚复合麻醉,观察组采用丙泊酚复合麻醉,比较两组简明精神状态量表(mini-mental state examination,MMSE)评分、警觉/镇静(observer assessment of sedation,OAA/S)评分、蒙特利尔认知评估量表(montreal cognitive assessment,MoCA)评分。结果 :两组术中出血量与手术、拔管、麻醉时间比较,差异无统计学意义(P> 0.05);术后,观察组MMSE评分、MoCA评分、OAA/S评分高于对照组,差异有统计学意义(P <0.05)。结论 :丙泊酚复合麻醉对行关节置换术老年患者的精神状态、认知功能影响更小。

Objective:To compare the anesthetic effect between sevoflurane combined anesthesia and propofol combined anesthesia in elderly joint replacement.Methods:100 elderly patients undergoing joint replacement admitted to our hospital from October 2017 to February 2019 were selected and randomly divided into two groups:a control group and an observation group,50 cases each.The patients in the control group were given sevoflurane combined anesthesia,and the patients in the observation group were given propofol combined anesthesia.The mini-mental state examination(MMSE)score,observer assessment of sedation(OAA/S)score and Montreal cognitive assessment(Mo CA)score were compared between the two groups.Results:There were no statistically significant differences in the volume of intraoperative bleeding during operation,extubation and anesthesia time between the two groups(P>0.05).After operation,the MMSE score,Mo CA score and OAA/S score in the observation group were higher than those in the control group,with statistically significant differences(P<0.05).Conclusion:Propofol combined anesthesia has less effect on mental status and cognitive function in elderly patients undergoing joint replacement.