基于CNKI数据库的国内线粒体动力学相关文献计量学分析

Bibliometric Analysis of Mitochondrial Dynamics in China Based on CNKI Database

目的分析国内发表的线粒体动力学的相关文献及发展趋势,为本领域科研人员提供参考以及新的科研思路。方法基于中国知网(CNKI)数据库,采用文献计量学的方法对目前国内有关线粒体动力学的文献进行统计分析,获得可视化信息。结果截至2017年8月20日共检索文献128篇,年度发文量自2011年以后增长明显,研究涉及学科广泛,主要集中在神经病学、精神病学、肿瘤学、心血管系统疾病等。中医药领域亦有较多的研究。"阿尔茨海默病""线粒体自噬""细胞凋亡"等关键词共现频次较高。结论国内对线粒体动力学的研究有待加强和深入,阐释阿尔茨海默病的发病机制、与线粒体自噬和细胞凋亡的交互作用可能成为线粒体动力学的研究热点和发展趋势。

Objective To analyze the related literatures and development trends of mitochondrial dynamics published in China,and provide reference and new research ideas for researchers in the field.Methods Based on China National Knowledge Infrastructure(CNKI)database,the literatures about the mitochondrial dynamics published in China were statistically analyzed by means of bibliometrics.The visual information was obtained.Results As of August 20,2017,128 articles were retrieved.The annual volume of publications had grown significantly since 2011.The research involved a wide range of disciplines,mainly in neurology,psychiatry,oncology,cardiovascular disease and so on.There are also many studies in the field of traditional Chinese medicine.Keywords such as'Alzheimer′s disease''mitochondrial autophagy'and'apoptosis'had a higher frequency of co-occurrence.Conclusion The research on mitochondrial dynamics needs to be strengthened and deepened.The pathogenesis of Alzheimer′s disease,interaction with mitochondrial autophagy and apoptosis may become a research hotspot and development trend of mitochondrial dynamics.