甲鱼蛋粉混合物对高脂模型大鼠血脂的影响

Effects of turtle egg powder mixture on serum lipids of experimental hyperlipidemia rats

目的 研究甲鱼蛋粉混合物 (红花油、维生素E、大蒜粉、甲鱼蛋粉 )对高脂血症大鼠血脂的调节作用。方法 将 5 0只健康雄性SD大鼠按体重和血清胆固醇水平随机分成 5组 ,分别接受正常饲料、高脂饲料、高脂饲料加甲鱼蛋粉混合物 (低、中、高剂量分别为 0 5、1 5、5 0g kgBW )灌喂处理 ,7周结束 ,测定血清胆固醇 (TC)、甘油三酯 (TG)低密度脂蛋白胆固醇 (LDL C)和高密度脂蛋白胆固醇 (HDL C)。结果 与高脂饲料组相比 ,甲鱼蛋粉混合物能降低高脂血症大鼠TC、TG和LDL C ,其中高剂量组具有显著性 (P <0 0 5 )。结论 研究结果表明甲鱼蛋粉混合物具有降低高脂血症大鼠血脂的作用。

Objective To study the lipid-lowering effects of a mixture composed of turtle egg powder, safflower oil, garlic powder and VE.Methods Fifty male SD rats were randomly divided into 5 groups according to body weight and serum cholesterol levels. They were fed one of five diets, a reference diet, a high fat supplemented diet (HF) and a HF diet supplemented with 0.5g/kgBW, 1.5g/kgBW and 5.0g/kgBW TEM. After 7 weeks, serum total cholesterol (TC), high density lipoprotein cholesterol (HDL-C) and triglyceride (TG) levels were determined by enzymatic methods on an automatic analyzer. Results Serum TC and TG levels were significantly decreased in the 5.0g/kgBW group compared with the HF rats (P<0.05), and at the same time, HDL-C level and its ratio to TC were not affected in groups fed high fat diet.