3磷化钙对人群致突变的观察研究

Study of Mutagenie Effect of Cajcium Phosphide on Human Groups

本研究应用姐妹染色单体互换和染色体结构畸变的方法,对磷化钙生产人员、熏蒸杀虫操作人员,以及经磷化钙熏蒸杀虫后再加工成食品的长期食用人员,进行了群体观察.结果表明:生产人员SCE及结构畸变明显高于用药人员及长期食用人员(P<O.01).而长期食用人员同对照组相比则无显著变化(P>O.05).

Sister chromatid exchange ( SCE ) and chromosomal structure aberration were studied in the following four groups : workers who produced calcium phosphide ( groupⅠ) ; workers who used calcium phosphide to fumigate corn to kill insect pests ( groupⅡ) ; inhabitants who ate the fumigated food for a long time ( groupⅢ) ; inhabitants who did not eat the food ( groupⅣ) .The results indicated that SCE and structure aberration of groupⅠ was significantly higher than those of groupⅡ and groupⅢ, while difference between groupⅢ and groupⅣ was not significant.