摘要
肼剂量在1.0、5.0和10.0mg/kg,甲基脐,剂量在0.5、2.0和5.0mg/kg对妊娠大鼠腹腔中毒(6～15天)无致畸胎作用.它们均引起胎鼠骨化过程延迟.另外,肼可引起明显的胚胎毒性.
Hz,at the dose of 1.0,5.0 and 10.0 mg/kg,MMH,at the dose of 0.5,2.0 and 5.0mg/kg had no teratogenic effects on fetuses when they were intraperitoneally administered to rats on the 6th to 15th day of gestation.They all induced retard of ossification of fetuses.In addition,Hz induced obvious embryotoxicity.
出处
《军事医学科学院院刊》
CSCD
北大核心
1989年第3期218-220,共3页
Bulletin of the Academy of Military Medical Sciences
关键词
肼
甲基肼
致畸胎
胚胎毒性
hydrazine
monomethylhydrazine
teratogenic effect
embryotoxicity
