自动静态视野随诊检查结果的可靠性研究

Reliability of successive automated static perimetry

目的 探讨青光眼与疑似青光眼患者自动静态视野随诊检查结果的可靠性。方法回顾性分析 1994年 8月至 2 0 0 0年 6月 ,使用Octopus 1 2 3全自动静态视野计连续检测次数≥ 2次的青光眼患者 (82只眼 )和疑似青光眼患者 (80只眼 )的视野检测资料 ,根据检测次数分为A、B、C组 ,比较各组患者视野检测结果的假阳性反应率 (FP)、假阴性反应率 (FN)及可靠性因子 (RF)。结果依据瑞士Interzeag公司提供的参考标准 ,疑似青光眼患者组 197份视野检测结果中 ,不可靠视野检测结果 10份 (5 1% ) ;青光眼患者 2 15份视野检测结果中 ,不可靠视野检测结果 39份 (18 1% )。青光眼患者各组的假阴性反应率远高于疑似青光眼患者 (P <0 0 1)。结论 多数疑似青光眼患者自动静态视野随诊检查结果可靠 ,少数不可靠的视野检测结果属偶然现象 ;假阴性反应结果与青光眼患者视野状态有关。

Objective The purpose of the present study was to explore the reliability of successive automated static perimetry in suspect and manifest glaucoma patients. Methods Retrospective investigation was performed on 82 glaucomatous eyes and 80 suspect glaucoma eyes which were tested twice or more during Aug 1994 and June 2000 with the Octopus 1-2-3 automated perimeter. False-positive response rate (FP), false-negative response rate (FN) and reliability factor (RF) were calculated and analyzed. Results According to the reference criterion provided by the manufacturer (Interzeag company), in suspect glaucoma patients, only 5.1% visual field test results (8 eyes) were unreliable, while the unreliable rate was 18.1% (20 eyes) in manifest glaucoma patients. FP, FN and RF all had highly skewed distributions in each subgroup of suspect and manifest glaucoma patients. The FN of each subgroup of manifest glaucoma patients was significantly higher than that of suspect glaucoma patients ( P <0.01). Conclusions Automated perimetry can provide a reliable result in most suspect glaucoma eyes. Α few unreliable results may be regarded as sporadic events. FN in glaucoma patients are related to the status of visual field defects.