心安颗粒对病毒性心肌炎患者心率变异性的影响

EFFECT OF XIN'AN GRANULES ON HEART RATE VARIABILITY OF PATIENTS WITH VIRAL MYOCARDITIS

目的 :观察心安颗粒对病毒性心肌炎患者心率变异性 (HRV)的影响。方法 :将 6 0例成人病毒性心肌炎患者随机分为治疗组和对照组 ,并设 30例健康组 ,治疗组服用心安颗粒每日 3次 ,每次 2包 ;对照组服用黄芪精口服液每日 3次 ,每次 10ml,7天为一疗程 ,连续 2个疗程。健康组不给予任何药物 ,各组均应用 2 4小时长程动态心电图监测分析HRV各时域指标 (SDNN、YMSSD、PNNSO、SDANN、SDNNindex、NRVI)。结果 :①病毒性心肌炎患者HRV与健康组比较有显著性差异 (P <0 .0 1) ;②治疗后 ,治疗组HRV各时域指标改善显著优于对照组 (P <0 .0 5 )。结论

Objective: To observe the effects of Xin'an Granules on heart rate variability (HRV) of patients with viral myocarditis. Methods: 60 viral myocarditis patients were randomly divided into treatment group which took Xin'an granules 2 packages t.i.d. and contrast group which took Huangqi jing oral liquor 10ml t.i.d, furthermore. 30 healthy people who took no drugs. To monitor and analyse the indexes of HRV (SDNN, YMSSD, PNN50,SDANN,SDNNindex,HRVI) in every group. Result: There were obvious differences betwecn treatment and healthy group (P<0.01); There was more obvious improvement in indexes of HRV in treatment group than contrast group after therapy (P<0.05).Conclusion: Xin'an granules make obvious improvement in viral myocarditis patients HRV.