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应用羊水板层小体计数预测胎肺成熟度 被引量:5

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摘要 羊水中板层小体(LB)富含卵磷脂,是肺表面活化物质合成与储存的场所。LB由肺泡Ⅱ型细胞排出后可附于胎肺泡腔表面,并随肺液流入羊水中,随着胎肺成熟,羊水中LB数量增多,据此可估计胎肺成熟度、预测呼吸窘迫综合征(RDS)发生率。该法在预测胎肺成熟度方面优于传统磷酯分析并有较高的阴性预测值。LB计数快速、省力、简单、廉价、客观,在有电子细胞计数仪的实验室均能开展,有很高的临床应用价值。
作者 杨桦 牛秀敏
出处 《国外医学(妇产科学分册)》 2004年第1期11-14,共4页 Foreign Medical Sciences(Obstet Gynecol Fascicle)
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  • 1Mulugeta S, Gray JM, Notarfrancesco KL, et al. Identification of lbm 180a Lamellar body limiting membrane protein of Alveolar type Ⅱ cells as the ABC transporter protein, ABCA3. J Biol Chem ,2002,277(25) : 22147-22155.
  • 2Zen K, Notarfrancesco K, Oorschot V,et al. Generation and characterization of monoclonal antibodies to alveolar type Ⅱ cell lamellar body membrane. Am J Physiol, 1998,275(1 Pt 1):172-183.
  • 3Samuels ER, Harrower T, Kahlon S, et al.Calcium-PS-dependent protein kinase C and surfactant protein A in isolated fetal rabbit type Ⅱ alveolar cells and surfactant-related material. Pediatr Pulmonol ,1999,27(2):95-103.
  • 4Wang PM, Fujita E, Bhattacharya J. Vascular regulation of type Ⅱ cell exocytosis. Am J Physiol Lung Cell Mol Physiol, 2002, 282(5):912-916.
  • 5Chander A, Sen N, Naidu DG, et al. Calcium ionophore and phorbolester increase membrane binding of annexin a7 in alveolar type Ⅱ cells. Cell Calcium. 2003.33(1):11-17.
  • 6Ansari MA, de Mello DE, Devaskar UP. Effect of prenatal glucocorticoid on fetal lung ultrastructural maturation in hyt/hyt mice with primary hypothyroidism. Biol Neonate, 2000,77(1):29-36.
  • 7Piazze JJ, Maranghi L, Nigro G, et al. The effect of glucocorticoid therapy on fetal lung maturity indices in hypertensive pregnancies.Obstet Gynecol, 1998, 92(2):220-225.
  • 8Stahlman MT, Gray MP, Falconieri MW, et al. Lamellar body formation in normal and surfactant protein B-deficient fetal mice. Lab Invest ,2000 , 80(3):395-403.
  • 9Guttentag S, Robinson L, Zhang P, et al. Cysteine protease activity is required for surfactant protein B processing and lamellar body genesis.Am J Respir Cell Mol Biol, 2003,28(1):69-79.
  • 10Weaver TE, Na CL, Stahlman M. Biogenesis of lamellar bodies, lyso-some-related organelles involved in storage and secretion of pul-monary surfactant.Semin Cell Dev Biol, 2002,13(4):263-270.

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