期刊文献+

妊娠肝内胆汁淤积综合征的遗传学研究进展

下载PDF
导出
摘要 妊娠肝内胆汁淤积症(ICP)病因复杂,遗传因素在发病机制中起相当关键作用。将胆汁淤积基因FIC、BSEP以及MDR3等作为ICP侯选基因,综述功能克隆、定位克隆及突变功能研究的进展。
出处 《国外医学(妇产科学分册)》 CAS 2004年第1期14-16,共3页 Foreign Medical Sciences(Obstet Gynecol Fascicle)
  • 相关文献

参考文献17

  • 1Savander M, Ropponen A, Avela K, et al. Genetic evidence of heterogeneity in intrahepatic cholestasis of pregnancy. Gut, 2003, 52(7):1025 - 1029.
  • 2Eloranta ML, Heinonen S, Mononen T, et al. Risk of obstetric cholestasis in sisters of index patients. Clin Genet, 2001,60(1 ): 42-45.
  • 3Elferink RO, Groen AK. Genetic defects in hepatoiliary transport.Biochim Bilphys Acta, 2002,1586(2): 129-145.
  • 4Jacquemin E. Role of multidrug resistance 3 deficiency in pediatric and adult liver disease: one gene for three diseases. Semin Liver Dis,2001,21(4): 551-562.
  • 5Elferink Ro. Cholestasis. Gut, 2003, 52 [Suppl 2]: ii42-48.
  • 6De Vree JM, Jacquemin E, Sturm E, et al. Mutations in the MDR3 gene cause progressive familial intrahepatic cholestasis. Proc Nat Acad Sci, 1998, 95 (1): 282-287.
  • 7Jacquemin E, Cresteil D, Manouvrier S, et al. Heterozygous non-sense mutation of the MDR3 gene in familial intrahepatic cholestasis of pregnancy. Lancet, 1999, 353 (9148): 210-211.
  • 8Jacquemin E, De Vree JM, Cresteil D, et al. The wide spectrum of multidrug resistance 3 deficiency: from neonatal cholestasis to cirrhosis of adulthood. Gastroenterology, 2001,120(6): 1448-1458.
  • 9Eloranta ML, Heiskanen JT, Hiltunen MJ, et al. Multidrug resistance 3 gene mutation 1712delT and estrogen receptor alpha gene polymorphisms in Finnish women with obstetric cholestasis. Eur J Obstet Gynecol Reprod Biol, 2002, 105(2): 132-135.
  • 10Milkiewicz P, Elias E, Williamson C,et al. Obstetric cholestasis. BMJ,2002,324(7330): 123-124.

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部