婴儿良性癫癎57例

Analysis of 57 children with benign infantile seizures

目的 探讨婴儿良性癫的临床特点、预后和早期诊断。方法 对 57例婴儿良性癫的临床资料进行分析。结果 发病年龄 1～ 3 0个月 ,发病前后发育正常 ,发作形式为强直 阵挛、双眼凝视和动作停止 ,64.9%呈成簇性发作 ,家族有癫、热惊厥史 6例。发作间期脑电图 (EEG)均正常 ,服用苯巴比妥 (PB)、卡马西平 (CBZ)或丙戊酸钠 (VPA)后发作很快被控制 ,51例已停药。发作终止年龄平均 12 .8个月 ,平均病程 4.1个月。结论 婴儿良性癫预后良好 ,短程服用PB。

Objective To detect the characteristics of benign infantile seizures.Methods Fifty seven cases of benign infantile seizures were analyzed.Results All patients had a normal development before and after the onset of the seizures.The age of onset was from 1.5-30 months.The main manifestations included tonic clonic seizure,staring and motion arrest,64.9 % occurred in clusters.A family history of epilepsy or febrile seizures was present in 6 cases.Interictel electroen cephalograms were normal.The seizures were easily ceased after taking phenobarbital,carbamazepine or valproate.Antiepileptic drugs(AEDs)were discontinued in 51 patients.The mean ages of seizure stopping were 12.8 months and mean seizure′s durations were 4.1 months.Conclusion The benign infantile seizures can be easily controlled with a single AEDs for short time with favorable prognosis.