摘要
为了研究姬松茸多糖对小鼠急性肝损伤的保护作用及其毒性反应,我们设计了两个试验方案:第一,先用四氯化碳(CCl4)攻毒后立即注射姬松茸多糖;第二,给小鼠注射不同高剂量的姬松茸多糖后在攻毒。结果表明:攻毒组GPT活性显著高于对照组,证实姬松茸多糖具有护肝作用;一定剂量范围内的姬松茸多糖未见有毒性反应,且对肝脏的保护呈现良好的量效关系。
In order to study the protective effect of ABM polysaccharide to liver of mice caused by CCl4 and its toxic effect We projected two tests: 1. Immediately injecting ABM polysaccharide to mice after CCl4 injury. 2. The mice was given different doses of ABM polysaccharide for 7 days before CCl4 injury. Conclusion: ABM polysaccharide had preventive effects against CCl4― induced liver injury in mice. 1～2 g/kg·BW ip ABM polysaccharide had no toxic effect on mice and 2 g/ kg·BW ip ABM polysaccharide had higher protection to liver injury than 1 g/ kg·BW ip ABM polysaccharide.
出处
《动物科学与动物医学》
2003年第11期21-22,共2页
Animal Science & Veterinary Medicine
