摘要
目的 :研究茵陈对大鼠肝UDP 葡萄糖醛酸转移酶 (UDP glucuronosyltransferase,UDPGT)活性的影响。 方法 :通过腹腔注射茵陈水溶液 ,从而建立大鼠肝UDPGT诱导模型 ,并以苯巴比妥为阳性对照 ,生理盐水为阴性对照 ,参照Black氏方法测定大鼠肝UDPGT活性。结果 :茵陈能够使大鼠肝UDPGT活性增加 ,肝 /体重比增大。结论 :茵陈能够诱导提高肝UDPGT活性 。
Objective:In order to investigate the influence of Herba Artiemisiae Capilloais on the UDPGT activity in rat's hepat.Methods: The UDPGT activities induced by Herba Artemisae capillaris were determined by the Black's assay.Results: Herba Artemisiae capillaris increased the activity of UDPGT in rats' hepat and also increased the ratio of liver weight/body weight. Conclusions: Herba Artemisiae capillaris was able to induce the acitvity of UDPGT in rats' hepat.
出处
《中成药》
CAS
CSCD
北大核心
2001年第1期45-47,共3页
Chinese Traditional Patent Medicine
基金
ck’sassay .Results:HerbaArtemisiaecapillarisincreasedtheactivityofUDPGTinrats’hepatandalsoin creasedtheratioofliverweight/bo
关键词
茵陈
UDPGT
酶诱导
Herba Artemisiae capillaris
Inducing
UDPGT
enzyme induction
