利用自建的活性肽数据库搜寻食物蛋白质中潜在的生物活性肽

Searching for Latent Bioactive Peptides Encrypted in Food Proteins with Self-Constructed Database of Biologically Active Peptides

利用MicrosoftOffice 2 0 0 0中的Access数据库软件建立了一个生物活性肽数据库 ,该数据库系统由生物活性肽序列及其相关信息子库、常见食物蛋白质序列子库和蛋白水解酶信息子库构成。同时数据库中引入了序列比对和酶解位点预测等 2个自编程序 ,利用该程序可分别用来寻找蛋白质中存在的生物活性肽片段或可能含有具有某种功能的生物活性肽的蛋白质及寻找把蛋白质中潜在的生物活性肽从该蛋白质中释放出来的适宜的酶。该数据库还具有数据的输入、修改删除、查询检索等功能。

By using Microsoft Access 2000 database software, a bioactive peptides database which was constructed which comprised three sub-database, ordinary food protein sequences sub-database and proteolytic enzyme information sub-database. Two self-developed programs provide flexibility in searching fragments of selected peptide or protein with the sequences of peptides from the database. Also it allows for searching enzyme that could hydrolysis the selected peptides. The daabase has functions for data input, data modification and deletion, query and search.