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藻酸双酯钠对脑血栓患者血小板功能的影响 被引量:2

Effect of polysaccharide sulfate on platelet functions in patients with cerebral thrombosis
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摘要 本文对27例脑血栓患者(男17例,女10例;年龄63±s8a)及20例正常志愿者对照组(男15例,女5例;年龄55±5a)测定β-血栓球蛋白(β-TG)及血小板因子4(PF_4)的血浆水平。发现脑血栓患者β-TG,PF_4的血浆水平明显高于对照组(P<0.01)。对其中8例脑血栓患者采用藻酸双酯钠(PSS)100mg加入10%葡萄糖500mL,iv,qd×10d后,血浆β-TG,PF_4明显降低(P<0.01)。 The plasma concentrations of B-thromboglobulin (B-TG) and platelet factor 4 (PF,) were measured in 27 patients (M 17, F 10; age 63 + 8 a) with cerebral thrombosis. Twenty healthy volunteers (M 15, F 5; age55+5a) served as control. Plasma B-TG and PF4 were significantly elevated in patients with cerebral thrombosis as compared with that of the controls (P<0.01). Polysaccharide sulfate (PSS) was used in 8 patients with cerebral thrombosis, 100 mg in 10% glucose 500 mL, iv, qd, 10 d as a course. The results showed that the plasma B-TG and PF4 were decreased significantly
出处 《新药与临床》 CSCD 北大核心 1992年第1期59-60,共2页
关键词 血小板功能 藻酸双酯钠 脑血栓 mucopolysaccharides/therapeutic use beta-thromboglobulin platelet factor 4
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