摘要
目的 探索红外热像扫描技术在组织工程皮肤移植修复中应用的可能性。方法 在组织工程皮肤对大面积皮肤缺损动物 (裸鼠 )进行移植修复的不同时间 ,应用红外热像扫描仪对移植修复区进行动态观察。结果 在移植术后第 7天 ,热像图上移植区与正常皮肤温差明显 (>0 7℃ ) ;在移植的第 14天 ,移植区与周围正常皮肤的温差变小(<0 3℃ ) ;在移植的第 2 1天 ,移植区与正常皮肤无明显区别 ,温度几乎没有差别 (<0 1℃ )。预示着移植区的血运、代谢情况与正常皮肤差别不大 ,移植区有毛细血管长入、营养供应充足。结论 在应用组织工程皮肤进行皮肤缺损的移植修复时 ,可以应用红外热像扫描技术对移植修复的效果进行动态观察 ,监测毛细血管的生成情况、血运状况以及移植的组织工程皮肤与宿主皮肤的融合情况。
Objective To study the application possibility of infrared-ray scan technique in observing the graft effect of tissue engineering skin.Methods Using infrared-ray scan technique observed the effect of tissue engineering skin grafted on nude mice which full-thickness wounded were made on the backs in the 7th, 14th and 21th day after grafting.Results On the 7th day after grafting, there was a obviously difference in temperature(>0.7℃) between grafted area and normal area; On the 14th day, the difference in temperature between grafted area and normal area had decreased(<0.3℃); on the 21th day, it could not find any difference in temperature(<0.1℃) between grafted area and normal area. It showed that the status of blood transportation and metabolism in grafted area were more similar to the nature skin. These results indicated that there was more crescent regenerative blood vessel appeared in the grafted area after grafting.Conclusion Infrared-ray scan technique can be used in observing the graft effect of tissue engineering skin.
出处
《中国实验诊断学》
2004年第1期40-42,共3页
Chinese Journal of Laboratory Diagnosis
基金
吉林省科委课题 ( 95 3 470 )
吉林省卫生厅课题 ( 2 0 0 0 0 44 )
