1Thun MJ, Namboodiri MM, Calle EE, et al. Aspirin use and risk of fatal cancer[J], Cancer Res, 1993,53(6) : 1322-1327.
2Jones DA, Cahon DP, McIntyre TMI et al. Molecular cloning of human prostaglandin endoperoxide synthase type Ⅱ and demonstration of expression in response to cytokines[J]. J Biol Chem, 1993,268( 12):9049-9054.
3Eberhart CE, Coffey RJ, Radhika A, et al. Up-regulation of cyclooxygenase 2 gone expression in human colorectal adenomas and adenocarcinomas[J]. Gastroenterology, 1994,107(14) : 1183-1188.
4Uefuji K, Ichikura T, Moehizuki H, et al. Expreasion of cyclooxygenase-2 protein in gastric adenocarcinoma [ J ]. J Surg Oncol, 1998, 69 ( 3 ) :168-172.
5Romano M, Riui V, Memoli A, et al. Helicobactor pylori up-regulates cyclooxygenase-2 mRNA expression and prostaglandin E2 synthesis in MKN28 gastric mucosal cells in vitro[J]. J Biol Chem, 1998,273( 44 ) : 28560-28563.
6DuBois RN, Shao J, Tsujii M, et al. G1 delay in cells overexpressing prostaglandin endoperoxide synthase-2 [ J ]. Cancer Res, 1996, 56 (4) :733-737.
7Sheng HM, Shao JY, Morrow JD, et al. Modulation of apoptosis and Bcl-2 expresion by pcostaglandin E2 in human colon cancer cells[J].Cancer Res, 1998,58(2) :362-366.
8Elder DJ, Halton DE, Hague A, et al. Induction of apoptotic cell death in human colorectal carcinoma cell lines by a cyclooxygenase-2 (COX-2)-selective nonsteroidal anti-inflammatory drug: independence from COX-2 protein expression [ J ]. Clin Cancer Res, 1997, 3 (10) : 1679-1683.
9Folkman J. What is the evidence that tumors are angiogenesis dependent[J]? J Natl Cancer Inst, 1990,82(1) :4-6.
10Hamada J, Cavanaugh PG, Lotan O. Seperable growth and migration factors for Large cell lymphoma, factors secreted by microvascular endothelial cells derived from target organs for metastasis[J]. Br J Cancer,1992,66(2) :349-354.
2Gustafson-Svard C,Lilja I,Hallbook O. Cyclooxygenase-1 and cyclooxygenase-2 gone expression in human colorectal adenocarcinomas and in azoxymethane induced colonic tumours in rats[J].GUT,1996,(01):79-84.doi:10.1136/gut.38.1.79.
3Ristimaki A,Honkanen N,Jankala H. Expression of cyclooxygenase-2 in human gastric carcinoma[J].Cancer Research,1997,(04):1276-1280.
4Witson KT,Fu S,Ramanujam KS. Increased expression of inducible nitric and cyclooxygenase-2 in Barret's esophagus and associated adenocarcinomas[J].Cancer Research,1998,(07):2929-2934.
5Xu XC. COX-2 inhibitors in cancer treatment and prevention,a recent development[J].Anti-Cancer Drug Design,2002,(02):127-137.
6Kay F,Folker F,Lisboa B W. CD44 isoforms correlate with celluar differentiation but not with prognosis in human breast cancer[J].Cancer Research,1995,(11):5424-5433.
7Tsujii M,Kawano S,Du Bois RN. Cyclooxygenase-2 expression in human colon cancer cells increased metastatic potential[J].Proceedings of the National Academy of Sciences(USA),1997,(07):3336-3340.doi:10.1073/pnas.94.7.3336.
8Joo M,Lee HK,Kang YK. Expression of E-cadherin,beta-catenin,CD44 and CD44v6 in gastric adenocarcinoma:Relationship with lymph node metastasis[J].Anticancer Research,2003,(2B):1581-1588.
9Gunthert U,Hofman M,Rudy W. A new variant of glycoprotein CD44 confers metastatic potential to rat carcinoma cells[J].Cell,1991,(04):13-25.doi:10.1016/0092-8674(91)90403-L.
10Waga S,Hannon GJ,Beach D. The p21 inhibitor of CDKs controls DNA replication by interaction with PCNA[J].Nature,1994,(16):574-578.doi:10.1038/369574a0.