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转录因子Egr-1及其在肺病变中的研究进展 被引量：10

The transcription factor Egr-1 and the lung diseases
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摘要 Egr-1 is an important transcription factor, which regulates at least 30 kinds of gene expression. Egr-1 couples extracellular signals to long-term responses by altering expression of Egr-1 target genes. So egr-1 can directly or indirectly affect cell differentiation,apoptosis,immune response,injury and repair. This article reviewed the progress in Egr-1 and the lung disease. Egr-1 is an important transcription factor, which regulates at least 30 kinds of gene expression. Egr-1 couples extracellular signals to long-term responses by altering expression of Egr-1 target genes. So egr-1 can directly or indirectly affect cell differentiation,apoptosis,immune response,injury and repair. This article reviewed the progress in Egr-1 and the lung disease.
作者 初令 曾庆富
机构地区 中南大学湘雅医学院病理学教研室
出处 《中国病理生理杂志》 CAS CSCD 北大核心 2004年第2期268-272,共5页 Chinese Journal of Pathophysiology
基金 国家自然科学基金资助课题 (No .30 170 399)
关键词 基因 即早 转录因子 肺疾病 Genes,immediate-early Transcription factors Lung diseases
分类号 R363 [医药卫生—病理学]
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参考文献32

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中国病理生理杂志
2004年 第2期

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