前列腺癌特异性抗原基因检测研究进展
摘要
前列腺癌是男性常见肿瘤之一 ,且前列腺癌患者逐年增加。为了适应临床早期检出原发性和潜在的转移性肿瘤的要求 ,前列腺癌特异性抗原 (PSA)的基因检测方法发展很快。而前列腺癌微转移检测在肿瘤早期诊断、治疗监测及预后判断方面具有重要意义。本文就PSA基因分子生物学。
出处
《国外医学(临床生物化学与检验学分册)》
2004年第1期13-16,共4页
Foreign Medical Sciences(section of Clinical Biochemistry and Laboratory Medicine
参考文献13
-
1Sourla A,Lembessis P,Mitsiades C,et al.Conversion of nested reverse-transcriptase polymerase chain reaction from positive to negative status at peripheral blood during androgen ablation therapy is associated with long progression-free survival in stage D2
-
2Gelmini S,Tricarico C,Vona G,et al.Real-time quantitative reverse transcriptase polymerase chain reaction for the measurement of prostate-specific antigen mRNA in the peripheral blood of patients with prostate carcinoma using the TaqMan detection system.C
-
3Grasso YZ,Gupta MK,Levin HS,et al.Combined nested RT-PCR assay for prostate specific antigen and prostate-specific membrane antigen in prostate cancer patients:correlation with pathological stage.Cancer Res,1998,58:1456-1459.
-
4Straub B,Muller M,Krause H,et al.Detection of prostate-specific antigen RNA before and after radical retropubic prostatectomy and transurethral resection of the prostate using ""Light-Cycler""-based quantitative real-time polymerase chain reaction.Urology
-
5Galvan B,Christopoulos TK.Quantitative reverse transcriptase-polymerase chain reaction for prostate-specific antigen mRNA.Clin Biochem,1997,30(5):391-397.
-
6Polascik TJ,Oesterling JE,Partin AW,et al.Prostate specific antigen: a decade of discovery what we have learned and where we are ging.J Urol,1999,162:293-306.
-
7Gomella LG,Raj GV,Moreno JG,et al.Reverse transcriptase polymerase chain reaction for prostate specific antigen in the management of prostate cancer.J Urol,1997,158:326-337.
-
8Mejean A,Vona G,Nalpas B,et al.Detection of circulating prostate derived cells in patients with prostate adenocarcinoma is an independent risk factor for tumor recurrence.J Urol,2000,163(6):2022-2029.
-
9Henke W,Jung M, Jung K,et al.Increased analytical sensitivity of RT-PCR of PSA mRNA decreases diagnostic specificity of detection of prostatic cells in blood.J Urol,2000,163(6):2022-2029.
-
10Ylikoski A,Sjoroos M,Lundwall A,et al.Quantitative reverse transcription-PCR assay with an internal standard for the detection of prostate-specific antigen mRNA.Clin Chem,1999,45(9): 1397-1407.
-
1糜远源,许斌,闵治超,邵宁,华立新,冯宁翰.肿瘤坏死因子相关凋亡诱导配体启动子区-716位点单核苷酸多态性与前列腺癌危险因素的研究[J].临床泌尿外科杂志,2011,26(2):143-146.
-
2巫志鹏,谭毅菁,刘芳,严爱芬,刘靖,黄文柱,唐冬生.电化学发光法检测前列腺癌特异性抗原标志物的研究[J].佛山科学技术学院学报(自然科学版),2014,32(6):36-40. 被引量:2
-
3常用肿瘤标记物筛检[J].健康必读(乡村医生),2011(5):9-9.
-
4杨柳,杨达荣,徐红梅,吴时军,米粲.雄激素受体在比卡鲁胺影响前列腺癌PSA表达中的作用及临床意义[J].现代检验医学杂志,2012,27(6):107-109.
-
5王进,马忠武,杨勇,冯娜,袁梅,陈琪,谢海浪.F-PSA、T-PSA、PSAD在前列腺癌诊断中的价值分析[J].江西医学检验,2007,25(3):283-283.
-
6袁泉良,屈中玉,任东方.血清PSA、ALP与OC联合检测在前列腺癌骨转移中的临床意义[J].中国卫生检验杂志,2015,25(23):4087-4089. 被引量:5
-
7前列腺癌将有新型早诊标志物[J].医药前沿,2015,0(5):3-4.
-
8毕金文.高水平PSA的40岁以下男性患者前列腺活检的回顾性研究[J].中国医药导刊,2011,13(6):966-967.
-
9杨桂凤,左书耀,王国明,王叙馥,张勤,武凤玉.骨显像诊断前列腺癌骨转移与病理分级及PSA的关系探讨[J].中国临床医学影像杂志,2010,21(1):72-73. 被引量:5
-
10史振铎,郝林,贺厚光,董洋,周家合,李志刚,赵岩,姜波,吕茜,刘颖,王洁,申友峰,何久香,韩从辉.hTERT/PSA在人雄激素非依赖性前列腺癌细胞株PC3中的表达[J].医药前沿,2017,7(9):92-93. 被引量:1