前列腺癌超声显像与病理组织学类型关系的研究

Relationship between ultrasonographic manifestation and pa thological histology type in prostate cancer

目的 探讨前腺癌超声表现和超声血流特征与病理组织学类型的关系。 方法 经手术证实的前列腺癌 (PCa)组患者 50例和良性前列腺增生 (BPH)组患者 50例 ,术前均行经直肠前列腺超声检查 ,将超声表现和血流特征与术后病理组织学类型进行比较并作统计学处理。 结果 PCa组超声主要表现为低回声结节 (62 % ) ,BPH组超声主要表现为混合回声结节 (54% ) ,两组差异有显著性意义 (P <0 .0 1)。低分化癌组和中分化癌组主要表现为低回声结节 (分别占 65%和 62 % ) ,高分化癌组主要表现为低回声结节 (54% )和混合回声结节 (3 6% )。PCa组前列腺结节区和外腺区的血管分布和血流信号与BPH组比较 :收缩期最大流速 (Vmax)分别为 15.2± 8.9和 10 .4± 4.1,血流阻力指数 (RI)分别为 0 .75± 1.4和 0 .69± 0 .2 ,差异有显著性意义 (P <0 .0 5)。 结论 PCa超声表现和超声血流特征在鉴别PCa和BPH方面有重要意义 ,掌握这些特征表现可提高前列腺癌的超声诊断水平。

Objective To assess the relationship betw ee n the ultrasonographic manifestation and the pathological histology type in pros tatic cancer. Methods 50 cases of CaP and 50 cases of BP H were included in this study.All the patients were ultrasonographic,and the dat a were compared with its the pathological histology type postoperatively. Results The typical ultrasonographic manifestation is hypoecho ic nodules (62%) in CaP group and mixed echo nodules (54%) in BPH group.There is a significant differences between CaP group and BPH group( P <0.01).There are mainly hypoechoic nodules (65%, 62%) in lower and middle differentiated cancer groups,and hypoechoic nodules and mixed echo nodules(54%,36%) in high different iated group.There is significant difference in distribution and the density of the flow signals (Vmax 15.2±8.9 vs 10.4±4.1,RI 0.75±1.4 vs 0.69±0.2) of pros tatic nodule area and outside area between CaP group and BPH group ( P <0.05). Conclusions Ultrosonographic exam plays a important rol e in distinquishing prostatic cancer from benign prostatic hyperplasia by ultras onographic manifestation and the flow signals.