52例e系统双阳性的乙型肝炎

52 CASES OF VIRAL HEPATITIS B WITH COEXISTING SERUM HBeAg AND ANTI-HBe

用酶联免疫吸附分析法检测了18734例乙型肝炎及其病毒携带者,其中e抗原e抗体同时阳性者52例,占0.27％。作者就e抗原e抗体同时阳性的临床意义作了讨论。

Coexistance of serum HBeAg and anti-HBe antibody is rarely seen in HBV-infected subjects. A series of 52 double positive cases for HBe system were (?)orted out of 18,734 HBY infected subjects in our hospitals from 1985 to 1990, the coexistance rate being 0.27%. The diagnosis of the series included 22 asymptomatic carriers, 3 acute hepatitis, 6 chronic persistent hepatits and 21 chronic active hepatitis, but no post-hepatitis liver cirrhosis er severe chronic hepatitis. The process of conversion from HBeAg positive to anti-HBe positive is discussed. The prognostic significance of coexisting HBeAg and anti-HBe in serum is analysed in connection with the clinical diagnosis and the results of liver function tests.