急性心肌梗死静脉溶栓疗效与血脂相关性

Plasma lipid analyse after intravenous thrombolysis in 38 patients with acute myocardial infarction

目的 :观察血脂水平对急性心肌梗死 (AMI)患者静脉溶栓治疗效果的影响。方法 :对 3 8例 AMI患者的总胆固醇 (TC)、甘油三酯 (TG)、低密度脂蛋白 -胆固醇 (L DL -C)及高密度脂蛋白 -胆固醇 (HDL -C)于发病后 2 4h内进行测定 ,以中华心血管病杂志编委会 ,AMI溶栓疗法参考方案为标准 ,分为再通组 (3 0例 ) ,未通组 (8例 )。结果 :溶栓再通组与未通组 TC、L DL -C、HDL -C比较差异无显著意义 ,未通组 TG明显高于再通组 (P<0 .0 5)。结论 :TG水平升高可能影响 AMI患者静脉溶栓效果 。

AIM: To investigate whether plasma lipid influences th e recanalization after intravenous thrombolysis in the patients with acute myoca rdial infarction (AMI). METHODS:38 cases of AMI patients with intravenous thrombolysis were divided into recanal ization group(30 cases) and non-recanalization group(8 cases). Plasma cholesterol (TC), tri glyceride(TG), low density lipoprotein-cholesterol (LDL-C), and high density lipoprotei n-cholesterol(HDL-C) were measured. RESULTS: TC, LDL-C, HDL-C in recanalization group and non-recanalization group had no statistical significance, TG level in non-recanaliz ation group was higher than recanalization group (P<0.05). CONCLUSION: TG in p lasma may have an effect on intravenous thrombolysis in the patients with AMI.