支气管动脉超选择性介入治疗中晚期肺癌

Super Selective Intervention of Bronchial Artery in Advanced Lung Cancer

目的 探讨支气管动脉超选择性介入化疗及栓塞治疗肺癌的疗效。方法 5 8例肺癌病人均行支气管动脉超选择性介入化疗栓塞术 ,观察治疗前后原发癌灶体积及最大直径与垂直直径的变化 ,比较肺CT影像学改变 ;观察栓塞剂用量与癌灶体积之间的关系 ;观察临床病征、介入并发症等情况 ,并进行分析。结果 支气管动脉超选择性介入化疗栓塞术治疗肺癌疗效显著 ,术后原发癌灶的体积大多有不同程度缩小 ,肿瘤最大直径与垂直直径乘积缩小 ,降低 5 0 %以上的占 89.6 6 % ,栓塞剂用量小 ,介入并发症出现率低 。

Objective To study the therapeutic effect of bronchial artery super selective interventional chemotherapy and embolization for lung cancer. Methods Fifty-eight patients with lung cancer were treated by bronchial artery super selective interventional chemotherapeutic embolization. The changes of volumes of primary malignancies, the product of maximal diameter and perpendicular diameter, CT imaging, clinical symptoms in pre and post treatment were compared and analyzed. The relation between the dosage of embolizing agent and cancer volume was also studied. Results The volume of primary lung cancer was decreased in various extents in most cases. In 89.66 % cases, the decrease of the product of cancer maximal diameter and perpendicular diameter was >50 % compared with pretreatment. Conclusion It demonstrates there is significant effect of chemotherapy and enbolization for lung cancer. It is effective in small dosage of embolizing agent with low complication rate and mild adverse effects.