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固相萃取柱上水解法合成^18F—FDG 被引量:3

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摘要 研究了一种新的固相萃取柱水解^18F—FDG中间体1,3,4,6-四-O-乙酰基-2-^18F—β—D-葡萄糖(^18F—FDG-DAc4)的方法。用活化过的C-18萃取柱捕获中间体^18F—FDG—Ac4,向柱中加入1mL 2mol/L的NaOH,室温下2min时99%以上的中间体可转化为^18F-FDG,加入磷酸缓冲液,再经C-18柱和三氧化铝柱纯化得到供注射用^18F—FDG。
出处 《同位素》 CAS 2003年第3期222-225,共4页 Journal of Isotopes
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