立体定向适形放射治疗体部肿瘤

Stereotactic conformal radiotherapy for extracranial tumors

目的 探讨立体定向适形放射治疗对体部肿瘤的疗效。 方法 1997年 5月～ 2 0 0 2年 8月立体定向适形放射治疗 86例体部肿瘤 (10 1个病变部位 )。肿瘤的临床靶体积 (clinicaltargetvolume,CTV) 0 2～ 2 32cm3 (平均 2 7 6cm3 ) ,计划靶体积 (planningtargetvolume,PTV)处方剂量 3～ 12Gy(平均 5 3Gy) ,分 1～ 10次照射。 结果 治疗过程中无死亡。患者一般状况评分 (Karnofskyperformancescores ,KPS) :治疗前 10～ 90分 (平均 6 0分 ) ,治疗后 2 0～ 10 0分 (平均 82分 )。随访 1～ 5年 ,完全缓解 (CR) 2 5例 ,部分缓解 (PR) 4 9例 ,无变化 (NC) 9例 ,进展 (PD) 3例。 结论 立体定向适形放射治疗体部肿瘤有较好疗效。

Objective To explore the curative effect of stereotactic conformal radiotherapy (SCR) for extracranial tumors. Methods Eighty-six patients with extracranial tumors underwent SCR from May 1997 to August 2002. The clinical target volume (CTV) of tumors ranged from 0.2 cm3 to 232 cm3, with a mean of 27.6 cm3. The prescribed dose to the planning target volume (PTV) was 3～12 Gy (mean,5.3 Gy),which were prescribed in 1～10 fractions. Results No patient died during the treatment. Karnofsky performance scores (KPS) ranged 10～90 (mean,60) and 20～100 (mean,82) before and after the treatment. Follow-up for 1～5 years showed complete remittence (CR) in 25 cases, partial remittence (PR) in 49 cases, no change in 9 cases, and progressed in 3 cases. Conclusions SCR is an effective method in the management of extracranial tumors.