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CD14与TLR2、TLR4在天然免疫中的相互作用 被引量：5

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摘要 CD1 4与Toll样受体 (TLRs)是天然免疫中重要的模式识别分子。CD1 4能够结合细菌内毒素脂多糖 (LPS) ,TLR2可以介导多种G+ 细菌细胞壁成分与细胞的反应 ,TLR4是介导LPS细胞内信号转导的关键分子。在天然免疫中CD1 4与TLR2 /TLR4协同作用 ,能够介导机体与多种病原体成分的反应。本文主要就CD1 4与TLR2
作者 江海燕 富宁
机构地区 第一军医大学免疫学教研室 第一军医大学免疫学教研室
出处 《国外医学（免疫学分册）》 2004年第2期112-116,共5页 Foreign Medical Sciences(Section of Immunology Foreign Medical Sciences)
基金 广东省自然科学基金项目 ( 0 0 10 5 8)
关键词 CD14 TLR2 TLR4
分类号 R392.11 [医药卫生—免疫学]
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参考文献40

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同被引文献93

  • 1蔡怡华,郑捷.Toll样受体与Th1和Th2型免疫应答[J].国际免疫学杂志,2006,29(5):295-299. 被引量：4
  • 2丁晶真,张蔚.绿茶成分心血管保护机制研究进展[J].药物流行病学杂志,2006,15(6):340-343. 被引量：8
  • 3Kaperonis E A, Liapis C D, Kakisis J D, et al. Infammation and atherosclerosis. Eur J Vasc Endovasc Surg, 2006, 31(4): 386-393.
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  • 6Youn H S, Lee J Y, Saitoh S I, et al. Suppression of MyD88- and TRIF-dependent signaling pathways of toll-like receptor by epigallocatechin-3-gallate, a polyphenol component of green tea. Biochem Pharm, 2006, 72(7): 850-859.
  • 7Pasterkamp G, Van Keulen J K, De Kleijn D P. Role of Toll-like receptor 4 in the initiation and progression of atheroselerotie disease. Eur J Clin Invest, 2004, 34(5): 297-299.
  • 8Vink A, Schoneveld A H, van der Meer J J, et al. In vivo evidence for a role of Toll-Like Receptor 4 in the development of intimal lesions. Circulation, 2002, 106(15): 1985- 1990.
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  • 10Xu X H, Shah P K, Faure E, et al. Toll-like receptor-4 is expressed by macrophages in routine and human lipid-rich atherosclerotic plaques and upregulated by oxidized LDL. Circulation, 2001, 104 (25): 3103-3108.

引证文献5

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国外医学（免疫学分册）
2004年 第2期

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