中西医结合治疗严重急性呼吸综合征临床分析

Clinical Study on Treatment of Severe Acute Respiratory Syndrome with Integrative Chinese and Western Medicine Approach

目的 :总结SARS患者一般临床特点 ,观察分析中西医结合治疗SARS的疗效。方法 :将 4 8例SARS确诊患者根据标准进行诊断分型 ,总结SARS患者一般基本特征、主要临床特点 ,并随机分入试验组2 4例及对照组 2 4例。对照组采用西医治疗方案 ,试验组采用中西医结合治疗方案。比较两组患者在病情进展速度、激素使用时间及肺部炎症吸收时间等方面的差异。结果 :18～ 4 0岁青壮年是SARS高发人群 ,首发症状以高热为主 ,可伴有全身肌肉酸痛、胸闷及咳嗽等症状 ;中西医结合治疗组患者在住院时间、体温波动持续时间及激素使用时间上较单纯西医治疗组短 ,差异有显著性 (P <0 0 5 ) ;在退热时间和肺部炎症吸收方面中西医结合治疗似较单纯西医治疗效果好 ,但无统计学意义。结论 :SARS患者以青壮年为主 ,发病时均有发热且可有伴随症状 ;中西医结合治疗较单纯西医治疗能明显缩短病程、防止体温反弹 ,缩短激素使用时间。

Objective:To summarize the clinical characteristics of severe acute respiratory syndrome (SARS) and observe the therapeutic effect with integrative Chinese and western medicine (ICWM) approach in treating patients with SARS. Methods:Forty-eight patients selected from the authors′ hospital, whose diagnosis confirmed as SARS were analysed to sum-up the diagnostic type and basic feature of patients and the chief clinical characteristics. All the patients were randomly divided into the trial group and the control group, 24 in each. The control group was treated with the western medical therapeutic program and the trial group was treated with ICWM therapeutic program. The differences between the two groups were compared in terms of development of illness, time of using corticosteroid and absorption time of pulmonary inflammatory lesion, etc. Results:Most patients were youth and adult aged between 18 to 40 years old, the initial symptom was mainly the high fever, accompanied with general soreness, chest stuffiness and cough, etc. The hospitalization time, body temperature fluctuation sustaining time and time of using corticosteroid in the trial group were shorter than those in the control group, showing significant difference (P<0.05). ICWM treatment showed a better effect in defervescence and inflammatory lesion absorption time, but with no statistical significance. Conclusion:Patients of SARS are mainly youth and adults in the prime of life, fever always appears as the initiation of illness and some accompanying symptoms would appear. As compared with the western treatment, ICWM treatment could evidently shorten the course of illness, prevent the rebounding of fever and reduce the time of using corticosteroid.