兔眼球透热术的实验研究

Experimental Study on Diathermocoagulation on Rabbit Sclera

分别采用酶联免疫吸附实验间接法及硫代巴比妥酸方法对实验性兔眼球透热术后房水的纤维连接蛋白及丙二醛进行了测定,并对术后组织病理进行了观察。表明兔眼术后房水中丙二醛含量明显升高,1周时达高峰,1个月时基本降到正常。房水中纤维连接蛋白含量3天至1周时下降明显。讨论了房水中丙二醛及纤维连接蛋白的含量变化及术后组织病理变化的意义。

After being diathermized,the fibronectin and malondialdehyde in the aqueous humorof the experimental rabbit eyeball were determined separately by means of ELISA andTBA.The histological and pathological changes were observed,too.Our results showedthat the concentrations of the malondialdehyde increased remarkably.It reached its peakvalue after a week and decreased to normal level after a month.The concentrations of thefibronectin decreased notably from 3rd day to 7th day after the operation.We also discussabout the significances of the histological changes,the pathological changes,and the cha-nge of the concentrations of the fibronectin and malondialdehyde.