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SICAM-1对慢性肝病及自发性细菌性腹膜炎的诊断价值 被引量:1

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摘要 目的 :探讨血清可溶性细胞间粘附分子 -1(SICAM -1)对慢性肝病及自发性细菌性腹膜炎诊断价值。方法 :采用ELISA法检测 10 6例慢性肝病及 2 5例正常血清SICAM -1水平 ,同期检测肝功能指标。结果 :CH (中 )、CH(重 )、Lc、CSH组SICAM -1显著高于正常对照 (P <0 .0 5 ,P <0 .0 1) ,Lc合并SBP显著高于Lc无SBP(P <0 .0 1)。相关性分析发现SICAM -1与总胆红素 (TBi)、谷丙转氨酶 (ALT) ,谷草转氨酶 (AST)呈正相关 ,与白蛋白 (ALB)呈负相关 ,预后差的慢性肝病患者SICAM -1水平较高。结论 :SICAM
作者 徐晓琦
出处 《中国交通医学杂志》 2004年第1期98-99,共2页 Chinese Medical JOurnal of Communications
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同被引文献11

  • 1吴月平,凌勇武,周艳,高金华,章幼奕,王为家,黄松平.慢性肝炎患者sICAM-1与肝组织病理变化的相关性研究[J].齐齐哈尔医学院学报,2004,25(8):866-867. 被引量:1
  • 2Kamezaki S,Kurozawa Y,Iwai N,et al.Serum levels of soluble ICAM-1 and VCAM-1 predict preclinical cancer[J].Eur J Cancer,2005,41(15):2355-2359.
  • 3Bataller R,Brenner DA.Liver fibrosis[J].J Clin Invest,2005,115(2):209-218.
  • 4Magness ST,Bataller R,Yang L,et al.A dual reporter gene transgenic mouse demonstrates heterogeneity in hepatic fibrogenic cell populations[J].Hepatology,2004,40(5):1151-1159.
  • 5Hellerbrand,Wang SC,Tsukamoto H,et al.Expression of intracellular adhesion molecule 1 by activated hepatic stellate cells[J].Hepatology,1996,24(3):670-676.
  • 6Pata C,Yazar A,Altintas E,et al.Serum levels of intercellular adhesion molecule-1 and nitric oxide in patients with chronic hepatitis related to hepatitis C virus:connection fibrosis[J].Hepatogastroenterology,2003,50(51):794-797.
  • 7Montalto G,Giannitrapani L,Soresi M,et al.Circulating intercellular adhesion molecule-1 in chronic hepatitis C patients with normal or elevated aminotransferase before and after alpha-interferon treatment[J].Intervirology,2003,46(1):35-42.
  • 8Benkoel L,Dodero F,Hardwigsen J,et al.Expression of intercellular adhesion molecule-1 (ICAM-1) during ischemia-reperfusion in human liver tissue allograft:image analysis by confocal laser scanning microscopy[J].Dig Dis Sci,2003,48(11):2167-2172.
  • 9张儒.细胞粘附分子与肝脏疾病[J].国外医学(消化系疾病分册),1998,18(3):152-155. 被引量:11
  • 10李东复,太京华,潘留兰,孟宪明,金珍婧,宋春莉.慢性肝病患者血清sICAM-1与TGF-β1水平及临床意义[J].中国免疫学杂志,2001,17(12):673-675. 被引量:6

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