番荔枝化学成分研究

STUDIES ON THE CHEMICAL CONSTITUENTS OF ANNONA SQUAMOSA

从番荔枝(Annona squamosa)中分离得到12个化合物,分别鉴定为liriodenine(AS—1),穆坪马兜铃酰胺(moupinamide,AS-2),-(-)-kauran-16α-01-19-oic acid(AS-3),16β,17-dihydroxy-(-)-kauran-19-oic acid(AS-4),anonaine(AS-5),16α,17-dihydroxy-(-)-kauran-19-oic acid(AS-6),(-)-isokaur-15(16)-en-17,19-dioic acid(AS-7),番荔枝酰胺squamosamide(AS-8),16α-methoxy-(-)kauran-19-oicacid(AS-9),sachanoic acid(AS-10),(-)-kauran-19-al-17-oic acid(AS-11),daucosterol(AS-12)。其中,番荔枝酰胺(AS-8)是新化合物,AS-9是第一次从植物中得到的天然产物。

Twelve compounds were isolated from Annona squamosa. Their struc-tures were identified as liriodenine ( AS-1), moupinamide (AS-2), -(-) -kauran-16α- ol -19 - oic acid(AS-3), 16β,17 - dihydroxy - (-) - kauran- 19 - oic acid(AS-4), anonaine (AS-5), 16α,17- dihydroxy- (-) - kauran - 19 - oic acid (AS - 6),(-)-isokaur- 15(16)-en- 17, 19-dioic acid(AS-7), squamosamide(AS-8), 16α- mcthoxy- ( - ) . kauran- 19- oic acid( AS-9 ), sachanoic acid(AS- 10 ), ( - )- kauran- 19-al- 17-oic acid(AS-11), daucosterol(As-12). Among them, AS-8is a new amide, AS- 9 is a new natural product.