沉香呋喃类立体异构体的气相色谱及气-质联用分析研究

STUDIES ON THE ANALYSIS OF STEREOISOMER OF AGAROFURANS BY GC AND GC-MS

采用GC及GC—MS方法,对沉香呋喃类中的三对差向异构体进行了成功的分离鉴定,确定了每对异构体的比例,建立了倍半萜类异构体的分析方法,从而有效地指导了合成反应,加快了合成的进度,为产物合成提供了可靠的依据。

The method for separation and identification of three pairs of agarofuran epimers(α-and β-dihydroagarofuran,α-and β-baimuxinol, α-and β-baimuxinol methyl ether) by HRGC andHRGC/MSD is described. The proportion of each pair of isomers was determined and the analyticalprocedure for isomers of sesquiterpenes was established. Thus, the correct synthetic route can be effc-tively guided and the study of agarofuran synthesis can be greatly accelerated. The method provides areliable basis for identifying the products. MS data given in Table 2 may be useful for the identifica-tion of agarofuran derivatives.