变应性鼻炎与支气管哮喘发病的相关性研究进展

Advancement in the pathogenic relationship between allergic rhinitis and asthma

变应性鼻炎 (allergicrhinits ,AR)与支气管哮喘二者常同时存在 ,前者先于后者发生 ,是哮喘的一个危险因素 ,故提出“一个呼吸道 ,一种疾病”的新概念。鼻病毒的感染、鼻 支气管反射、上呼吸道机能的改变均是AR对哮喘影响的因素 ;治疗AR会改善肺功能 ,降低气道高反应性 ,减轻哮喘。本文简述AR与哮喘间的密切联系 ,以期拓宽临床医生对二者间相互联系的认识 。

It has been noted that allergic rhinitis (AR) and asthma often co exist. Furthermore, AR will be a risk factor for asthma if AR precedes to asthma. Hence the concept of 'one airway, one disease' was proposed. Infection of rhinoviruses, naso bronchial reflex, and dysfunction of the upper airway all contribute to the effect of allergic rhinitis on asthma. The treatment of allergic rhinitis can improve the pulmonary function, reduce bronchial hyperresponsiveness, and improve symptoms of asthma. Here, we analyze and summarize the close relationship between AR and asthma based on literature review so as to shed light on the clinical practice.