2001年诺贝尔医学奖对中医药基础研究的启发

Inspiration to basic researches of traditional Chinese medicine from the 2001 Nobel Prize

20 0 1年哈特韦尔、纳斯与亨特三位诺贝尔生理学或医学奖获得者的贡献揭开了细胞周期调控的神秘面纱 ,对开辟治疗癌症新途径将具有极其深远的意义 ,同时对中医药基础研究亦有很大的启发。他们对肿瘤发生发展的认识 ,从过去的静态观转向动态地辩证分析 ,从单一的研究转向多方面整体综合分析 ;对肿瘤的治疗 ,强调的是调节而不是杀伤 ,并且认为驱动细胞周期正常运转的众多因子中 ,实质上只有正调和负调两大类因子。这些观点与中医学的辨证论治、整体治疗、阴阳平衡理论十分相似 ,为中西医结合架起了科学理论的鹊桥 。

The contributions of the three winners (L Hartwell, RT Hunt and PM Nurse) of the 2001 Nobel Prize for physiology or medicine revealed the mystical veil of cell cycle control. It was of far-reaching significance for exploring new method for cancer treatment. It will also give a good deal of enlightenment to the basic research of traditional Chinese medicine. Their understanding about the cause and development of cancers changed from the static view to dynamic dialectical analysis, from simplex study to comprehensive analysis; they stressed regulation, instead of killing in the treatment of cancer; and they thought that the numerous factors driving the normal process of the cell cycle could be summarized as positive and negative factors. These opinions were similar to some theories of traditional Chinese medicine, such as treatment based on syndrome differentiation, integrative treatment, and keeping the balance between yin and yang, and established a connection between traditional Chinese medicine and the western medicine, which would further widen the research on compound prescriptions of Chinese herbs.