用高效液相色谱法测定咳清胶囊中磷酸可待因的含量

Determination of Contents of Phosphoric Acid Codeine in Keqing Capsules with High Performance Liquid Chromatography

目的 :以咳清胶囊为研究对象 ,建立对罂粟壳中所含磷酸可待因含量的测定方法。方法 :采用高效液相色谱法。结果 :回归方程为C(μg) =1 1 5 4 84× 1 0 - 6A +0 0 0 0 0 6 6 5 7,相关系数r =0 9999,线性范围为0 1 6～ 0 80 μg ,平均回收率为 96 6 1 % ,RSD为 1 70 % (n =6 )。 结论 :本法快速 ,简便 ,回收率高 。

Objective: To determine the content of phosphoric acid codeine in opium. Methods: Using high performance liquid chromatography. Results: The test results from 3 sets of samples met our expectation. Conclusions: This method is quick, simple and convenient. The recovery rate is high, and the result is accurate and reliable.[