A Styrylpyrone Dimer from the Bark of Goniothalamus leiocarpus
A Styrylpyrone Dimer from the Bark of Goniothalamus leiocarpus
摘要
A dimer of styrylpyrone derivative, leiocarpin E (1), was isolated from the bark of Goniothalamus leiocarpus. Its structures was elucidated by means of spectral and chemical methods. The cytotoxicity of leiocarpin E against HL-60 cells was tested.
A dimer of styrylpyrone derivative, leiocarpin E (1), was isolated from the bark of Goniothalamus leiocarpus. Its structures was elucidated by means of spectral and chemical methods. The cytotoxicity of leiocarpin E against HL-60 cells was tested.
参考文献9
-
1[1]Q. Mu, C. M. Li, H. J. Zhang, Chin. Chem. Lett., 1996, 7, 617.
-
2[2]Q. Mu, C. M. Li, H. D. Sun, Chin. Chem. Lett., 1999,10, 135.
-
3[3]C. M. Li, Q. Mu, H. D. Sun, Acta Botanica Yunnanica, 1999, 20, 102.
-
4[4]S. K. Talapatra, K. Basu, T. D. S. Goswami, Indian Journal of Chemistry, 1985, 24B, 29.
-
5[5]X. P. Fang, J. E. Anderson, C. J. Chang, Tetrahadron, 1991, 9751.
-
6[6]Q. Mu, W. D. Tang, Y. Lu, Heterocycles, 1999, 51 (12), 2969.
-
7[7]Leiocarpin E 1 C26H24O6 mp 251-252°C, UVλmaxnm (log ε): 204.5 (3.40); IR (KBr)ν 3343 (OH), 1707, 1638, 1451, 1210, 817, 761 cm-1; FABMS m/z: 433[MH]+; EIMS m/z (%): 433 (2) [MH]+, 414 (0.5) [M-H2O]+, 335 (4), 305 (100), 209 (60), 115 (22), 97 (99).
-
8[8]10 mg of leiocarpin C was acetylated (AC2O-pyridine; 24h, room temp.), and the mixture was partitioned between ice water and CHCl3. The CHCl3 extract on concentration showed one spot one TLC and purification by chromatography afforded compound 2. Acetatylleiocarpin E (2) EIMS m/z (%): 474 (4) [M]+, 414 (60) [M-AcOH]+, 377 (5), 317 (10), 305 (100). FABMS m/z: 475 [MH]+.
-
9[9]S. Wang, Y. J. Zhang, R. Y. Chen, J. Nat. Prod., 2002, 65, 835.
-
1Qing MU,Chao Ming LI,Yi Neng HE,Han Dong SUN,Hui Lan ZHENG,Yang LU,Qi Tai ZHENG,Nan WU,Ren Wang JIANG(Phytochemistry Laboratory, Kunming Institute of Botany, the Chinese Acadmy of Sciences,Kunming 650204)(Institute of Meteria Medica. Chinese Academ.Three New Styrylpyroncs from Goniothalamus leiocarpus[J].Chinese Chemical Letters,1999,10(2):135-138.
-
2Qing MU,Rong Wei TENG,Chao Ming LI,De Zu WANG,Yu WU,Han Dong SUN,Chang Qi HU.Leiocyclocin A and B, Two Cyclopeptides from Goniothalamus leiocarpus[J].Chinese Chemical Letters,2001,12(7):607-610. 被引量：1
-
3Jiang, Z,Yu, DQ.Donhexocin,a New Non-tetrahydrofuran Acetogenin from Goniothalamus Donnaiensis[J].Chinese Chemical Letters,1997,8(3):233-234.
-
4Chen, Y,Chen, RY,Yu, DQ.A New Annonaceous Acetogenin from Goniothalamus Gardneri[J].Chinese Chemical Letters,1997,8(11):971-974.
-
5Qing MU,Chao Ming,LI Hong,Jie ZHANG,Yu WU and Han Dong SUN(Kunming Institute of Botany, Chinese Academy of Sciences,Kunming 650204).A NEW STYRYL-LACTONE COMPOUND FROMGONIOTHALAMUS LEIOCARPUS[J].Chinese Chemical Letters,1996,7(7):617-618. 被引量：1
-
6Fan XU,Xue Qin CAO,Zhi Gang YAO,Zheng Bai CAO(Department of Chemistry, Suzhou University. Suzhou, 215006)Jian CHEN(Testing and Analysis Centre, Fudan University, Shanghai, 200433).Synthesis and Structure of 2,3-Tetra-Methylene-5,6-Trimethylene-4-Pyrone[J].Chinese Chemical Letters,1997,8(4):275-276.
-
7New Alkaloids from the Rhizomes of Goniothalamus Griffithii[J].Chinese Chemical Letters,1998,9(11):0-0.
-
8CAO Xue-Qin,ZHANG De-Chun,XU Fan CAO,Zheng-Bai(Department of Chemistry, Suzhou University, Suzhou, 215006)SUN Ji(Shanghai Institute of Organic Chemistry,the Chinese Academy of Sciences, 200032, Shanghai).Molecular and Crystal Structure of 2, 3, 5, 6-dipropylene-r-pyrone[J].Chinese Journal of Structural Chemistry,1997,16(4):271-274.
-
9林樱姬,黄卫丹.提高香豆素产率的方法研究[J].大连民族学院学报,2006,8(1):96-96.
-
10Chi ZHANG,Xue Chao WANG,Fang Ning ZHANG and Xin Fu PAN(Department of Chemistry, State Key Laboratory of Applied Organic Chemistry Lanzhou University, Lanzhou 730000 ).A FACILE TOTAL SYNTHESIS OF 6-PENTYL-α-PYRONE[J].Chinese Chemical Letters,1996,7(4):317-318.
