诱发电位在多发性硬化诊断中的价值

Values of evoked potential in the diagnosis of multiple sclerosis

目的 :评价诱发电位在多发性硬化 (MS)诊断中的价值 ,并为临床提供MS的诱发电位(EP)资料。方法 :本课题采用临床病例分析统计方法 ,对 16 4例MS患者的 3项EP资料进行分析。结果 :MS患者的 3项EP中 ,视觉诱发电位 (VEP)的异常率最高 ,其次为体感诱发电位 (SEP) ,脑干听觉诱发电位 (BAEP)最低 ;这 3项EP联合检查可使异常率提高 ,EP发现病灶的敏感性较临床检查高 ,其不仅可以发现中枢神经系统的病灶 ,而且还能够发现外周神经系统的病灶。结论 :联合应用

Objective:To evaluate the value of evoked potentials (EP) in the diagnosis of multiple sclerosis (MS) and provide the EP information of multiple sclerosis for clinicians.Methods:The data of evoked potential were analyzed retrospectively in 164 patients with multiple sclerosis by means of clinical statistis.Results:The abnormality rate of visual evoked potential in multiple sclerosis was the highest (75%),and that of samtoscnsory evoked potential was the second high(69%),however,the abnormality rate of brainstem auditory evoked potential was the lowest (67.5%).The abnormality rate increased as the three kinds of EP were combined.The evoked potentials were more sensitive in detecting focus than clinical examinations.EP could detect not only the focus in central nervous system but also in periphcral nervous system.Conclusions:Combination of different kinds of evoked potential might be helpful in the diagnosis of MS and detection of subclinical focus.