聚乙二醇电解质散中氯化钾、碳酸氢钠的含量测定

Assay for KCI and NaHCO_3 in Macrogol Electrolytes Powder

目的 建立测定聚乙二醇电解质散中氯化钾和碳酸氢钠混合物含量的方法。方法 二步滴定法。先用0.1 mol/L盐酸滴定液滴定碳酸氢钠,再用0.1 mol/L硝酸银滴定液滴定氯化钾的二步滴定法。结果 以检验量的80％、100％、120％取样,进行试验,碳酸氢钠和氯化钾的平均回收率分别为99.92％(RSD=O.15％)和99.53％(RSD=0.45％)。精密度试验,RSD分别为0.11％和0.36％(n=8)。结论 本方法是一种新的氯化钾、碳酸氢钠混合物的含量测定方法,简便、经济、实用。

Objective To establish a method to determine the content of KC1 and NaHCO3 in Macrogol Electrolytes Powder. Methods Twi-titration assay was used. To titrate NaHCO3 with 0.1 mol/L hydrochloric acid VS firstly and then , to titrate KC1 with 0.1 mol/ L silver nitrate VS. Results On the basis the examination quantity of 80% , 100% , 120% ,The average recovery rate of KC1 and NaHCO3 were 99.92% ( RSD=0.15%) and 99.53%( RSD=0.45%), the precision were 0.11% and 0. 36% (n=8). Conclusion This method is a new way for assay of mixture KCl and NaHCO3. It is sinple, cost, saving and practical.