银杏叶制剂与阿司匹林联合治疗单纯性糖尿病视网膜病变

Ginkgo biloba preparation combined with aspirin in treating diabetic retinopathy

目的 :评价银杏叶制剂与阿司匹林联合应用对糖尿病视网膜病变的疗效。方法 :将 5 6例糖尿病视网膜病变的病人分为 2组 ,在基础治疗相同的情况下 ,治疗组 32例给予银杏叶制剂 2片 ,每日 3次 ,同时口服阿司匹林 0 .1g ,每日 1次 ;对照组 2 4例 ,加用阿司匹林 0 .1g ,每日 1次 ,2组均治疗 3mo。观察治疗前后的眼底变化及血胰岛素、血脂、血液流变学指标的变化。结果 :治疗组总有效率为88% ,对照组总有效率为 6 2 % (P <0 .0 5 ) ,治疗组治疗后血糖 ,胰岛素、血脂、血液流变学指标有明显改善 (均P <0 .0 1) ,2组治疗后血糖 ,胰岛素 ,TG ,HDL及血液流变学指标的差值比较差异有显著意义 (P <0 .0 5或P <0 .0 1)。结论 :银杏叶制剂与阿司匹林联合应用对糖尿病视网膜病变有较好治疗效果。

AIM: To investigate the effects of Ginkgo biloba preparation combined with aspirin for diabetic retinopathy. METHODS: fifty-six patients with diabetic retinopathy were divided into two groups. Under the same basic treatment, the treatment group with thirty-two patients was treated with Ginkgo biloba preparation and aspirin; twenty-four patients were only treated with aspirin . The methods had been applied to the two groups for three months . The effects of Ginkgo biloba preparation and aspirin on serum insulin , blood lipid, hemorheology were observed. RESULTS:The total effective rate of treatment group was 88% ; and that of control group was 62% ( P<0.05) . After treatment, the concentrations of fasting blood glucose (FBG), insulin, blood lipid and hemorheology were dropped remarkably (P<0.01) in the theatment group. There was significantly difference in the indexes of fasting blood glucose ,insulin ,TG,HDL and hemorheology between treatment group and control group after treatment (P<0.05 or P< 0.01). CONCLUSION: Ginkgo biloba preparation combined with aspirin has good effects on diabetic retinopathy .