摘要
以亚磷酸二乙酯为磷酰化试剂,通过Atherton-Todd反应分别对邻间对苯二酚和氨基苯酚6种化合物进行了磷酰化改造。通过此方法得到了其相关磷酰化衍生物,并首次给出了相关磷酰化产物的波谱数据。
The Atheron-Todd reaction has been applied extensively to the synthesis of phosphates and phosphoroamidates. In this study, aminophenols and dihydroxybenzenes were phosphoylated by a modified Atheron-Todd procedure, in which DEPH and tetrachloromethane were added to the mixed solution of phenol, triethylamine and dioxane and the mixed solution of phenols, triethylamine and dioxane, respectively. The target phosphates were obtained with good yields. Their structures were elucidated by NMR and ESI-MS.
出处
《波谱学杂志》
CAS
CSCD
北大核心
2004年第1期87-91,共5页
Chinese Journal of Magnetic Resonance
基金
国家自然科学基金(39870415)
2001河南省省拨院士基金
关键词
苯二酚
磷酰化
氨基苯酚
亚磷酸二乙酯
核磁共振
波谱分析
NMR, ESI-MS, phosphorylation, aminophenols, dihydroxybenzenes, diethyl phophite (DEPH)
