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精子特异性透明质酸酶PH-20结构与功能 被引量:6

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摘要 精子表面特异性透明质酸酶(PH-20)是糖基磷脂酰肌醇(GPI)锚定的单链膜蛋白,特异性分布于精子头部浆膜和顶体内膜,是一种多功能蛋白,在受精过程中具有重要作用。鉴于PH-20在精子表面的特异性分布及其在受精中的作用,PH-20作为免疫避孕候选疫苗对象一直受到关注。继续深入研究PH-20的结构与功能,将有助于全面揭示精卵结合的分子过程。
出处 《国外医学(计划生育分册)》 2004年第1期5-7,共3页
基金 福建省重点科技攻关项目(2002Y032)资助
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