QT间期离散度及P波离散度与小儿扩张型心肌病预后的关系

Relationship between QT interval dispersion,P wave dispersion and the prognosis of the children with dilated cardiomyopathy

目的 探讨QT间期离散度 (QTd)及P波离散度 (Pd)与小儿扩张型心肌病 (DCM)预后关系。方法 5 2例DCM患儿 (研究组 ) ,男 31例 ,女 2 1例 ,年龄 3个月～ 18岁 ,平均 (5 79± 5 17)岁 ,死亡 5例。随机匹配健康儿童 5 2例为对照 (对照组 )。受检对象描记 12导联同步体表心电图 ,选择波形清晰的 3个心动周期自动分析合并人工干预测量心率 (HR)、QTd与Pd。结果 研究组较对照组心率增快 (P <0 0 5 ) ,P -R间期 (P <0 0 5 )、QRS间期 (P <0 0 1)及QTc间期 (P <0 0 1)延长 ;QT max增加 (P >0 0 5 ) ,QTd、Pmax、Pmin及Pd延长 (P <0 0 1)。死亡组与存活组比较QTd与Pd无差异 (P >0 0 5 )。结论 QTd和Pd在DCM患儿明显增大 ,但其对估测DCM预后价值有限。

Objective To probe relationship between QT interval dispersion (QTd),P wave dispersion (Pd) and the prognosis of the children with dilated cardiomyopathy (DCM).Methods 12-lead simultaneous body surface electrocardiogram were taken from 52 cases with DCM (research group) aged from 3 months to 18 years old (mean 5.79±5.17 years) and 52 healthy children as control (control group).The HR,QTd and Pd were tested by hand during three clear waves cycles in electrocardiograms.These data were statisticsed by computer with SPSS 11.0 software.Results Compared with control group,HR increased ( P <0.05),P-R duration prolonged ( P <0.05),QRS duration and correct QT interval (QTc) increased ( P <0.01),QTmax prolonged ( P >0.05) ,QTd,Pmax,Pmin,Pd increased ( P <0.01) in research group. There was no difference in QTd and Pd between death group and survival group.Conclusions QTd and Pd of DCM markedly prolong,but its value is limited to evaluate the prognosis of DCM.