成人肝肉瘤8例临床分析

Sarcoma of the Liver in Adults:Clinical Analysis of 8 Cases

目的 探讨成人肝肉瘤的临床特点及治疗方法。方法 回顾性分析 8例成人肝肉瘤的临床资料。结果 8例成人肝肉瘤患者 (平滑肌肉瘤 6例 ,枯否氏细胞肉瘤 2例 )均行探查术 ,并获随访。 3例切除肿瘤者生存时间分别为 2 0 ,3 9,70个月。未能切除肿瘤者 5例 ,其中 2例行介入治疗者生存时间分别为 7、10个月 ,1例手术探查后行全身化疗者生存 2 2个月 ,2例未行任何治疗者生存时间分别为 5、7个月。结论 成人肝肉瘤无明确病史及基础疾病 ,血清学检查无特异性 ,通过物理学检查方法早期发现 ,手术切除治疗是最为有效的治疗方法 。

Objective To discuss the clinical characteristics and treatment of sarcoma of the liver in adults.Methods 8 cases of sarcoma of the liver in adults,treated from 1980 to 2001,were analyzed retrospectively.Results In the 8 cases,6 cases were smooth muscle sarcoma,2 cases Kupffer sarcoma.All were treated with surgical operation and followed up.The survival time of 3 cases with complete resection were 20 months,39 months and 70 months respectively.5 cases did not recieve complete resection.2 cases with intervent ionaltherapy were alive for 7 months and 10 months respectively.1 case with chemotherapy after laparotomy was alive for 22 months.The other 2 cases without any treatment were alive for 5 months and 7 months respectively.Conclusion The sarcoma of the liver in adults is a rare disease without evident past history and basic disease.There is no specific serum tumor marker.The early diagnosis is made mostly by diagnostic therapy.Surgical resection is the most effective therapy,whereas chemotherapy should also be considered.