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军人人格因素与ACE基因多态性相关性研究 被引量:6

CORRELATION BETWEEN SERVICEMEN PERSONALITIES AND THE POLYMORPHISM OF ACE GENE
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摘要 为了探讨军人人格特质遗传因素的理论依据 ,为制定科学有效的心理干预措施提供参考 ,选择 16种人格因素问卷测查和聚合酶链反应 (PCR)检测血管紧张素转换酶 (ACE)基因多态性 ,对 13 0 6名军人进行了 16种人格因素问卷与ACE基因型的相关性研究。结果显示 ,ACE基因多态性与女军人人格因素中的恃强性、敢为性、独立性、自律性人格因素有较高的相关性 ;与男军人人格因素中的恃强性、敢为性、独立性、稳定性、实验性因素有较高的相关性。 To explore the theoretical basis of the heretability of servicemen's personalities and to provide references for the development of a set of scientific and effective psychological interventions, 1 306 servicemen were subjected to the 16-PF inventory questionaire and polymerase chain reaction (PCR) examination of angiotensin. The results showed that there was a significant correlation between the scores of self-will, social boldness, self-reliance, and self-restraint in the female servicemen, and the scores of self-will, boldness, self-reliance, emotional stability, and openness in the male servicemen were significantly correlated with the DD genotype of the ACE gene. The results suggested that the determination of the DD genotype of the ACE gene could be used as a useful tool in the research of heretability of personality factors.
机构地区 解放军总医院
出处 《解放军医学杂志》 CAS CSCD 北大核心 2003年第7期606-607,共2页 Medical Journal of Chinese People's Liberation Army
基金 全军"十五"指令性课题 (编号 0 1L0 4 8)
关键词 16-PF 人格特质 血管紧张素转换酶 基因多态性 PF personality angiotensin I-converting enzyme genotype
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  • 1[1]Hubbert C, Houot AM, Corvol P et al. Structure of the angiotensin I-converting enzyme gene: two alternate promoters correspond to evolutionary steps of a duplicated gene. J Biol Chem, 1991,266:15 377
  • 2[2]Badehop RF, Wang XL ,Wilken DE et al. Angiotensin-converting enzyme genotype in children and coronary events in their grandparents. Circulation, 1995, 91(6): 1 655
  • 3[3]Mario R, Ehelrs W, Riordan JF. Angiotension-converting enzyme: new concepts concerning its biological role. Biochemistry, 1989,28:5 318

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